Sentence examples for median effect on from inspiring English sources

The median effect on heart rate increased from placebo to 0.3 mg epinephrine as i.m. injection over 4 to 8 mg inhalative epinephrine (Fig.  2).

Conclusions: We defined the overall median effect of furosemide on urine output, urinary sodium, potassium and chloride losses and fluid balance in critically ill patients and provided information on how such effects were modulated by mean arterial pressure and albumin levels.

Consolidated graphs of the median effects of LY2878735 on several endpoints are provided in Figure 6.

The median effect plot (based on the logarithmic form of Chou's median effect equation) forms the basis of quantification of synergism, summation and antagonism of drug combinations: log (fraction affected/fraction unaffected) vs. log (Dose).

The synergy analysis based on the median effect methodology developed by Chou and Talalay [ 39] could not be performed on the in vivo data because the combination was only tested at one dose of gefitinib.

Drug combination effects were determined using the Chou and Talalay method (Chou and Talalay, 1984) based on the median effect principle.

Drug combination effects were determined using the Chou and Talalay method as described elsewhere (Chou and Talalay, 1984) based on the median effect principle.

Drug interactions were analyzed using CompuSyn 3.0.1 (ComboSyn, Inc.,Paramus, NJ), which is based on the median effect model of Chou and Talalay [ 23].

This methodology is based on the median effect equation correlating drug and its effects and is used to derive an accurate value of relative potencies of different drugs (e.g. IC50 etc).

Many drug combination assays use the combination-index isobologram method, which is based on the median effect principle developed by Chou and Talalay (1984), but this method tests fixed dose ratios of the two drugs, and we wished to investigate the full interaction surface across a broad range of concentrations of both drugs.

The median effect size was 1.46, which corresponds (on some reasonable assumptions) to a decrease in aggression of about one quarter.