Sentence examples for median coverage depth from inspiring English sources

As a result, 367 contigs were generated with a 29-fold median coverage depth.

Median coverage depth for each sample varied between 75 and 254 (median = 129, n = 168).

This sample was sequenced to a median coverage depth of 91X as part of the Melbourne Genomics Health Alliance demonstration project.

Illumina MiSeq sequencing was performed following manufacturer's user manual (Illumina) to generate FASTQ files, resulting in median coverage depth of 500 700x for each sample.

This was indicated in our data by the significant decrease of contig numbers as the median coverage depth increased (R = 0.69, p < 0.0001, Additional file 1: Figure S1A).

Median coverage depth for determined positions was variable but typically high (range 21 to 156×) (Table 1, [also see additional file 1]).

Figure 2 shows ROCs generated by varying the threshold τ with a fixed α = 0.05. Figure 2a shows ROC curves for a true 0.1% MAF for a range of median coverage depths.

Given that the mean and median of coverage depth across positions generally fails to provide a useful metric due to extensive variation across genomic loci, one practical measure that researchers rely upon is the fraction of target positions that are covered at greater than or equal to a given depth (e.g. 20×).

Mapping of FSL R2-574 system system reads to the F2365 reference genome resulted in 200× median unique coverage depth, with unique coverage gaps only in multicopy loci (e.g., rRNA genes).

Similarly, average or median coverage statistics may relate to sequencing depth, but non-uniform expression may make comparisons between them less informative than for genome assemblies [ 20- 22].

Median coverage is reported for determined positions (≥ 2× coverage depth) in reference-guided analysis.