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As in the previous figures, 101 simulations were performed for each trial and the median clone sizes are presented.
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TP53 mutations with a median clone size of 11% were detected in 10 patients (18%) at an early stage [ 26].
In control epidermis, the median clone size (50% ranking in Figure 6E; "+" in Figure 6H) was similar in IFE, HF, junctional zone, and infundibulum but significantly smaller in the SG (p < 0.05, two-tailed unpaired Mann-Whitney test).
Asterisk indicates that this sample had less purity, and hence clone sizes are estimates.
Minimum 50 clones and maximum 150 clone sizes were analyzed in this experiment.
This phenomenon can be understood by analysing the clone sizes of the 200 selected clones.
As expected, control clones that only overexpressed GFP had variable clone sizes (Fig 3B and C).
Clone sizes were then estimated by statistical approaches [ 22, 46].
When we overexpressed Yki in the sd MARCM clones, the clone size is much smaller than the Yki overexpressed clones.
Clone size calculations were determined as previously described [12].
They statistically analyzed shear site data to estimate clone size.
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