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An interaction between offspring and control status was present at the medial tibial site (P <0.01).
The maximum underestimation was 3.3% at the medial tibial site with one in four slices (Table 2).
Cartilage defects predicted cartilage volume loss at the medial tibial site only; however, this did not persist after adjustment for meniscal damage.
In this study, baseline cartilage defects predicted cartilage volume loss at the medial tibial site only; however, this did not persist after adjustment for meniscal damage.
This is consistent with our recent observation in sibling pairs that the rate of cartilage loss had high heritability, especially at the medial tibial site [ 24].
Changes in medial and lateral tibial BMLs were significantly associated with change in pain, with the association stronger among offspring at the medial tibial site (P value for interaction was <0.01).
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In the medial compartment, the contact points shift toward the medial tibial spine, a region where degeneration is observed in patients with chronic anterior cruciate ligament injuries.
Similarly, in longitudinal analysis, compared to the cartilage volume change using 1.5 mm thick slices, decreasing the number of the slices by extracting one in two to one in four slices led to very little over or under estimation of the mean changes in cartilage volume at lateral, medial tibial and patellar sites (Table 4).
In cross-sectional analysis, compared to the cartilage volume measured using 1.5 mm thickness, decreasing the number of the slices by extracting one in two to one in four led to a very little underestimation in the magnitude of the average cartilage volume at lateral, medial tibial and patellar sites with ICCs of 0.98 1.00 (Table 2).
At baseline and the first follow-up, participants were given a BML score (mm) for each of the four sites (medial tibial, medial femoral, lateral tibial, and lateral femoral sites) as well as a total BML score, which was the sum of the scores at each site.
aNo BML present at baseline and follow-up (n = 212) versus incident BML (n = 14) at any site (medial tibial, medial femoral, lateral tibial, and lateral femoral).
More suggestions(15)
medial tibial condyle
medial tibial exostosis
medial tibial eminence
medial tibial subsidence
medial tibial collapse
medial tibial cartilage
medial tibial surface
medial tibial side
medial tibial physis
medial tibial tray
medial tibial paBMD
medial tibial growth
medial tibial stress
medial tibial compartment
medial tibial spine
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