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This medial olfactory artery becomes the ACA proper in an 11.5 to 18 mm embryo, while the terminal portion of the PO ℓA usually regresses.
Komiyama [ 25] and Okahara et al. [ 6] stressed that the PO ℓA terminates in the nasal fossa, and "secondary artery" constitutes the medial olfactory artery, which supplies the olfactory bulb.
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We previously found that rats learn to self-administer amphetamine into the medial olfactory tubercle [38].
One of the groups received vehicle injections into the medial olfactory tubercle throughout the experiment.
In an open field, we did not detect reliable difference in facilitating locomotion and rearing between the medial olfactory tubercle, medial shell and core [42].
The involvement of the medial olfactory tubercle in reinforcement is consistent with the previous finding that cocaine injections into the medial olfactory tubercle induce conditioned place preference [37], [49].
We examined whether contingent administration of amphetamine into the medial olfactory tubercle without visual signals increased lever pressing.
The vicinity of the medial olfactory tubercle appears to be most responsive to this function of amphetamine.
Each rat received noncontingent amphetamine administration into the medial olfactory tubercle on a 90-sec fixed interval schedule.
Thus, both schedules delivered the same amount of amphetamine into the medial olfactory tubercle in the 90-min session.
Thus, this experiment suggests that amphetamine administration into the medial olfactory tubercle or in its vicinity is reinforcing.
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