Sentence examples for mechanistic work and from inspiring English sources

His early work involved the development of organo-nickel coupling reactions and nucleophile addition to metal-activated aromatic rings, including both mechanistic work and applications in the synthesis of natural products.

Grosser thinks that the breadth of clinical research opportunities at Penn, encompassing genomics, mechanistic work, and animal modeling, makes such career setbacks less likely.

These data complement our mechanistic work and support a role for NKX2.2-mediated transcriptional repression in Ewing's sarcoma oncogenesis.

ML and EBJ were responsible for design of the AhR transcriptional activity study and preparation of the manuscript; ML performed the mechanistic work and data evaluation.

Even though surgery was designed with the aim of causing mechanical restriction and calorie malabsorption, mechanistic work in humans and rodents over the last 10 years or so has informed us that this could not be further from the truth.

This review highlights the recent structural and mechanistic work on amino acid heterocyclization, peptide cleavage and peptide macrocyclization.

A large region of genomic amplification on chromosome 8q was found to be most strongly linked to activation of the CSR profile, and mechanistic work indicated that over expression of resident 8q genes Myc and COP9 was sufficient to activate the CSR signature.

Although most of the structural and mechanistic work to date has been performed on the Mcm2-7 complex from yeast and Drosophila, the strong evolutionary conservation of Mcm2-7 makes it likely that findings with lower eukaryotes will also apply to human DNA replication.

Theoretical and mechanistic work has contributed important insights into the design of modified cyclooctynes with enhanced reactivity.

Refocusing and planning efforts in the QTN programme must take into careful consideration not only these broader contexts, but the experimental resolution of available methods, their inference space and generality (Rockman 2012), and whether the outcome will generate a starting point for the essential mechanistic work advocated by Travisano and Shaw (2012).

Much of the mechanistic work to date on phthalates and allergy has focused on DEHP and its ability to modulate responses to allergens (Jaakkola and Knight 2008; Kimber and Dearman 2010).