Sentence examples for mechanistic understanding based from inspiring English sources
DOI: http://dx.doi.org/10.7554/eLife.01519.023 The mechanistic understanding based on the cognate substrate analog-bound structure suggests a crucial role for the cross-subunit Gly- cisPro motif in enantioselectivity and rejection of L-aas from the pocket.
Discussion is based on mechanistic understanding, specifically kinetics based on hydrogen assisted CO dissociation; a linear relationship between CH4 and C5+ products; possible reinsertion of olefins; hydrogenation of olefins; and surface coverage based on SSITKA data.
Therefore, a mechanistic understanding has been based often on analogy and speculation.
Therefore, being able to account for this destabilization in structural and dynamics terms is critical for a mechanistic understanding of base selectivity.
Models that are based on mechanistic understanding yet remain within the bounds of data-based parameter estimation can accommodate rigorous and complete error analysis.
Results were interpreted according to behavioral models based on mechanistic understanding of leaching processes.
Finally, prospective about the rational design, mechanistic understanding and application of BOC based materials is demonstrated, aiming to broaden the perspective and provide guidelines for future work.
Synthesis of a variety of well-shaped chiral ligands as well as design of catalysts based on mechanistic understanding enable the creation of the reactive and selective catalysts with a broad substrate scope.
While empirical process development techniques will continue to play an important role in addressing these challenges, approaches based on mechanistic understanding are likely to be more impactful for solving the more complex multidimensional problems by providing insights into the interplays between the cell line, bioprocess, and product quality.
The chosen model was originally published in [ 31, 40], and it is based on mechanistic understanding of the corresponding biochemical system.
Numerous studies have reported on genetic variations modifying the clinical radiosensitivity risk, predominantly in pathways based on mechanistic understanding of the radiation pathogenesis (reviewed in [ 11]).
