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The reprogrammed cyclization cascades of EIZS mutants result from divergent mechanistic sequences that branch from a handful of key carbocation intermediates, such as the farnesyl cation, the (4 R -bisabolyl cation, oR -bisabolyl or (7 R)-homobisabolyl cation.
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Then, he sequences that.
Therefore, one may speculate that hyperglycaemia induces microglial death that, synergistically with endothelial iNOS, induces neuronal apoptosis, suggesting a mechanistic sequence to account for sepsis associated brain dysfunction.
The hydrophobic active site contour of EIZS serves as a template that enforces a single substrate conformation, and chaperones subsequently formed carbocation intermediates through a well-defined mechanistic sequence.
These observations suggest a mechanistic sequence for the origin of eukaryotes.
"Regulatory agencies are putting a lot of effort into understanding the sequence of mechanistic events that lead to disease.
Conversely, some sorting systems have more or less obvious similarities at the sequence and the mechanistic level that indicate that the sorting pathways have also diversified by duplication and co-option of their components.
Because the energy model is derived from explicitly mechanistic (i.e., energetic) first principles, it is sensitive to many potential features of DNA sequence that allow or inhibit local nucleosome formation.
We previously suggested that the propensity of IS elements to occupy intergenic sequences might be a consequence of a mechanistic bias that prevents IS elements from interrupting essential genes (Clayton et al. 2012).
Enumerate the mechanistic abnormalities that may be predisposing to aspiration in this patient.
However, the mechanistic features that determine miRNA-mediated silencing efficacy remain poorly understood.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com