Sentence examples for mechanistic problems from inspiring English sources

Understanding the biology of the CAR IS will be a powerful approach to efficiently guide the engineering of new CARs and help identify mechanistic problems in existing CARs.

Based on the obtained results, we conclude that local models are useful to solve specific mechanistic problems among one group of ILs, but in case of predicting the toxicity for a new designed compound the global model, whenever fulfills all quality recommendations, is recommended.

Taken together, the new paradigms have been shown to solve fundamental molecular mechanistic problems in bioenergetics and motility and to offer a most detailed, unified and appealing picture of energy generation, transduction, storage and utilization processes in systems of biological molecular machines.

In addition to addressing these phylogenetic questions with new genomic information, we further address several mechanistic problems relevant to phylogenetic reconstruction.

Using these three matrices, we explored several key mechanistic problems of phylogenetic reconstruction including missing data, matrix selection, gene and taxa number/choice, and the biological function of the genes.

This point of view has been tremendously influenced by Max Weber's theory of rationalization (Hill 1981), which emphasizes that running an organization and managing human resources are a mechanistic problem in nature.

The quest to account for all mutational signatures is as much a mechanistic problem as it is epidemiological.

This is mainly due to the mechanistic problem that such an allele cannot be genetically linked with the fittest cytotype 5, 6, 44.

In 2007, Jonsson et al published a "reanalysis" of a mechanism-based PK/PD model of neutropenia, which was the first example of the fully transparent application of MCMC Bayesian methods to a complex, hierarchical mechanistic PK/PD problem.

Neuropsychology Review is a quarterly, refereed publication devoted to integrative review papers on substantive content areas in neuropsychology, with particular focus on populations with endogenous or acquired conditions affecting brain and function and on translational research providing a mechanistic understanding of clinical problems.

The authors might consider referring to such complexities, perhaps in the context of their statement that "the existence of analogy shows that, at least, for numerous and diverse biochemical problems, unrelated mechanistic solutions can evolve".