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Our results have established that these β-sheet-correlated motions provide mechanistic pathways that can allow functional transitions between distal sites.
In this work we propose a mechanism based on parallel hydrogen-assisted mechanistic pathways that leads to a LH model with the denominator term, k'CO*PCO where k'CO is effectively an activated rate constant instead of an equilibrium constant and therefore increases with increasing temperature instead of decreasing.
The catalytic promiscuity of the CO mimics to perform CC bond coupling, hydrolase, nuclease, catalase and PHS activity suggests the potential of such mimics may extend beyond the biological modeling and provide insight to the various possible mechanistic pathways that may be adapted by a model complex.
Few studies have examined the mechanistic pathways that may explain masked hypertension.
In this manuscript, we focus on the link between the extent of microbial Fe(III) reduction and mineralogical changes, and discuss mechanistic pathways that are responsible for the changes.
Consequently, the focus of this study is to investigate the alteration of ferruginous smectite in systems with active DIRB-clay interactions with and without O2 as the TEA, and to discuss mechanistic pathways that yielded the observed secondary mineral assemblages.
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Ultimately, it is these biomarkers that are on the mechanistic pathway that will offer the greatest value for enhanced drug development and personalized medicine.
This suggests a mechanistic pathway that amplifies the effects of occupational exposures.
These results suggested a mechanistic pathway that needs to be further investigated.
To examine one mechanistic pathway that might be responsible for the inhibition of cisplatin-induced apoptosis, the protein expression of AKT was studied.
Using small molecule inhibitors, the biosensor cellular assays with microfluidics also enable mechanistic deconvolution of signaling pathways that lead to receptor desensitization.
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