This requires a re-orientation of disease-specific interventions away from mechanistic logic-models and towards realistic assessments of the complex, social and adaptive nature of health systems at all levels, and highlights once more the importance of careful planning and adequate investment in both system hardware and software to achieve sustained and quality service-delivery at all levels.
Applying a mechanistic, Cartesian logic to water, the currency of life, ignores the ecological impacts of diverting and transporting water over long distances, or mining water from the ground beyond its recharge rates.
In the development process of SS Rotterdam, the mechanistic and rational logic was only modestly developed.
This dual role of TGF- β1 in cancer has long been noted, but its mechanistic basis, operating logic, and clinical relevance have remained elusive.
Without clarification of this mechanistic point, the logics of the argument presented in the paper are confusing and unclear, making it difficult to make a decision concerning the paper.
Whereas outstanding genetic work in yeast has led to rapid discovery of a large number of interacting genes involved in the control of mitotic exit, it has also become increasingly difficult to comprehend the logic and mechanistic features embedded in the complex molecular network.
In this study, we assumed that there is no precise knowledge about the contractile behavior of an isolated artery, which can form the basis for an expert-designed fuzzy logic system or mechanistic model.
The development of technology challenges this logic, as it draws this mechanistic optimization to its natural limits by offering to rationalize everything that can be rationally optimized.
In contrast to physicochemical ODE models that are based on mechanistic descriptions of the biochemical processes, these logic-based ODE models can be seen as continuous representation of qualitative biological knowledge [ 18].
The mechanistic nature of computation is a recurring theme in logic, philosophy, and cognitive science.
This example shows that the logic-based ODE model, although not using mechanistic kinetics, is in principle able to give rise to different complex dynamics depending on the choice of the parameters (which, as in all ODE models, must be determined or estimated from experimental data).
