Sentence examples for mechanistic justification for from inspiring English sources

However, as yet there has been no mechanistic justification for either assumption and, since quantifying fitness effects of epistatic interactions between multiple resistance or virulence genes empirically is notoriously difficult, it is not known which types of epistasis tend to naturally occur in the wild [for related discussion see 6].

The current study indicates that effective inhibition of the Wnt/β-catenin pathway in CRC cells expressing FAK and PYK2 will only be achieved by simultaneously targeting both kinases, which provides a solid mechanistic justification for clinical use of FAK/PYK2 dual inhibitor instead of FAK-specific inhibitor for better clinical outcomes in CRC patients.

(2013) may explain the recognized risk for secondary cancers in such patients following external beam radiotherapy and genotoxic chemotherapy, for which a mechanistic justification has thus far been lacking (Kleinerman et al., 2012; Wong et al., 2014).

Such a through-flux has earlier been postulated in the literature, but with unrealistic mechanistic justification.

Understanding the fundamental behaviors of organic molecules, how structure relates to reactivity, was sufficient justification for such mechanistic explorations, a testament to a time when society was more forgiving of curiosity-driven science.

Ginkgo biloba leaves have been used for many centuries in traditional Chinese medicine and justification for quercetin supplements is historical rather than mechanistic.

There is no compelling evidence-based justification for a general low-exposure linearity; rather, case-specific mechanistic arguments are needed.

Spatial autocorrelation also highlights the importance of proper sampling design of point measurements of soil respiration and provides strong justification for including additional factors such as vegetation cover and aboveground leaf biomass in future mechanistic models of soil respiration.

Justification for research.

Justification for Buying a Kindle.

There is no justification for terror".