Sentence examples for mechanistic intervention from inspiring English sources

However, the possibility that the HBE acts through a mechanistic intervention rather than an in vitro direct physical interaction with the venom is also a reasonable idea.

It is particularly intriguing that the dramatic mechanistic intervention by TCBQ reductase has a large effect on the rate at which dehydration of the C4a-hydroxyflavin can occur, but only a 2-fold effect on kcat.

If not mentioned otherwise, the mechanistic and intervention studies addressed in this paper utilized a ≈1000 ± 50 mg/m3 × min delivery over a 30-min exposure period.

For mechanistic and intervention studies, actual concentrations were determined in real time using a calibrated Gasmet Dx-4000 FT-IR (Fourier transform infrared spectroscopy) gas analysis system (for details see http://www.gasmet.com/images/tiedostot/product-downloads/Gasmet_DX4000_Technical_Data_ v1.6 .pdf //www.gasmet.com/images/tiedostot/product-downloads/Gasmet_DX4000_Technical_Data_ v1.6 .pdf

This progress has resulted from the use of standardized study designs, endpoints, and, to a certain extent, mechanistic analyses in intervention trials in the setting of new-onset T1D.

Further, the data suggests new mechanistic points of intervention for 2ME2 in RA, specifically inhibition of inflammatory mediators and osteoclast activity.

Owing to these underlying mechanistic differences, therapeutic interventions for treating muscle dysfunction in ARDS may differ during the early and late phases.

These interactions shed a light on biological pathways that link the signature genes to disease parameters and provide mechanistic insight into interventions effects.

Through the identification of differentially expressed miRNAs in patients who developed shock, these data provide new directions of exploration into both mechanistic discovery and therapeutic intervention.

34 They differ from explanatory trials in that pragmatic trials are meant to inform decisions about practice rather than explain mechanistic aspects of an intervention under ideal circumstances.

A large multicenter randomized control trial is required to determine the efficacy and to shed insights on the underlying mechanistic effect of this intervention before it can be used routinely for septic shock patients.