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What are the possible mechanistic interpretations for the destabilizing event?
The influence of environmental stress on children's health can be assessed by biomonitoring studies in maternal and umbilical cord blood using validated biomarkers of exposure, early genetic effects, and genetic susceptibility, in combination with new approaches, for example, (epi genomics to facilitate mechanistic interpretations (for review, see Vineis and Perera 2007; Wild 2005).
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Even when modeling leads to the characterization of particular molecule fragments related to toxicity, it is not easy to build a precise mechanistic interpretation for their role in biological activity (see for example [19]).
In addition, it could provide a mechanistic interpretation for the effector-mediated activation.
In the light of all this and of the recent evidence that Th17 cells play a role in immune-mediated control of tumors [38], [39], [40], our results may provide a mechanistic interpretation for the observed coupling of protective antitumor immunity with autoimmunity during IFN-α therapy.
Our data presented here may have provided a mechanistic interpretation for their findings.
Finding a mechanistic interpretation for these alterations is important to understand pathophysiological processes, however it is not an easy task.
Furthermore, there is no obvious mechanistic interpretation for why the inhibition strength should be different with cellobiose and pNPG or MUG.
The data available so far do not allow any mechanistic interpretation for this phenomenon, but this observation indicates again that the A. blazei extract is able to exert metabolic effects.
By fitting a two-state model to the experimental data, we provided a mechanistic interpretation for the clone-to-clone diversity of expression patterns, in terms of differences in chromatin dynamics.
Moreover, it suggests a mechanistic interpretation for varying levels of anesthesia-induced unconsciousness, where disrupted thalamo-cortical functional connectivity, but intact cortico-cortical functional connectivity reflects lighter states of unconsciousness and disruptions of both cortico-cortical and thalamo-cortical functional connectivity reflect deeper states of unconsciousness.
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