Sentence examples for mechanistic hypothesis based from inspiring English sources

Herein, we support the quest for a selective catalyst for ethanol electro-oxidation to CO2, building on our previous mechanistic hypothesis based on experimental insight and DFT computations.

Since they were not part of any of our original mechanistic hypotheses based on Sawada et al.'s work, however, we exclude the M1, M3 and M5 receptors from the discussion which follows.

Finally, chemoinformatic methods can help generate high-yield mechanistic hypotheses based on relevant compounds identified by chemical biology approaches.

Exposure models also provide the opportunity to better understand key mechanistic processes in the source receptor relationship and the model predictions (hypothesis based) can be evaluated with monitoring data (test derived) (Cowan-Ellsberry et al. 2009; Sheldon and Cohen Hubal 2009).

Such lack of correlation could be explained by different mechanistic hypotheses all based on structural features of mRNAs that would enable complex physiological regulation, which here is stress-responsive regulation.

The authors advance a mechanistic hypothesis in which excess base would form an N-fluoroammonium KCO3– salt intermediate, in which the KCO3– triggers fluorodesilylation of the substrate and would be followed by the enantioselective transfer of fluorine to the substrate.

This analysis, based on genomic methods, yielded new information that can be used for generating a mechanistic hypothesis for further study of perinatal exposure of PDBE using traditional methods of toxicology.

One mechanistic hypothesis is tumor necrosis, which would lead to a weakening of the intestinal wall [17].

One mechanistic hypothesis of anthracycline-induced cardiotoxicity (ACIC) relates to oxidative damage and mitochondrial dysfunction, which leads to cardiomyocyte apoptosis (Fig. 1).

Experimental approaches stemmed from this mechanistic hypothesis may thus open new avenues for developing novel inhibitors to attack the multidrug resistance mediated by AcrB-like transporters.

These results are surprising as they conflict with the mechanistic hypothesis and experimental evidence that mTOR inhibition decreases VEGF levels [30, 33, 34].