Sentence examples for mechanistic function in from inspiring English sources

Thus APC's key mechanistic function in the destruction complex remains largely unknown.

Therefore it is likely that cep-1/p53 has a different mechanistic function in C. elegans tumors from gld-1 and glp-1 [ 28, 44] mutants compared to mammals [ 45].

We found that ARF recapitulates its core mammalian mechanistic functions in zebrafish cells and tissues.

Despite an increasing number of studies on the biogenesis and mechanisms of miR-22 in the pathogenesis of GC, the accurate expression and mechanistic function of them in GC remain elusive.

55 The mechanistic function of PDK1 in breast cancer has also been investigated.

While we fully accept that we cannot exclude indirect effects of REV1 deficiency, addressing the details and mechanistic function for REV1 in kataegis is beyond the scope of this paper, and will require extensive additional work.

Taken together, we propose a model (Fig. 12) for the mechanistic function of Notch signaling in stem cell differentiation: Notch signaling activates the transcription of LSTF as well as Hes/Hey proteins.

By combining Ca2+ measurements in A. niger mutants with deregulated cAMP/protein kinase A (PKA) signaling, we proved the interconnection of Ca2+ perturbation and cAMP/PKA signaling in the mechanistic function of PAF.

The flavivirus nonstructural glycoprotein NS1 is a cell surface protein (soluble entity) that generates neurovirulence in host neural cells after peripheral inoculation of virus, a multifunctional protein that shows mechanistic function [ 115] and assists the virus in neuronal invasion [ 116].

Our study further underline that this mechanistic function of the antifungal protein PAF is common in sensitive fungi.

The mechanistic function of this activity is only poorly understood.