Sentence examples for mechanistic dissection of from inspiring English sources
The E50K optineurin transgenic mouse described here exhibited clinical features of POAG and may be useful for mechanistic dissection of POAG and therapeutic development.
A mechanistic dissection of early oocyte differentiation in vertebrates is key to advancing our knowledge of germline development, reproductive biology, the regulation of meiosis, and all of their associated disorders.
Given their relative simplicity, these single-subunit OSTs (ssOSTs) have emerged as important targets for mechanistic dissection of poorly understood aspects of N-glycosylation and at the same time hold great potential for the biosynthesis of custom glycoproteins.
The short life span of MEF cells has necessitated repeated passaging for reprogramming cells onto new feeders, making mechanistic dissection of the reprogramming process difficult.
A further mechanistic dissection of these isolates based on whole genome sequence analysis could shed some light on their genome evolution trends and the extent of HGT occurring within the rfb cluster that encodes much of the surface antigens responsible for determination of their serotype.
10.7554/eLife.05920.021 Figure 4. Mechanistic dissection of harmine.
These mechanistic dissections of Na+ channel blockers during neuroinflammatory disease have provided an evidence-based recruitment of patients in either PPMS, SPMS or RRMS for clinical phase trials in the US and the UK [ 98].
If the comparison between gonadectomized males and females reveals a sex difference, further mechanistic dissection can be achieved by determining whether sex chromosomes or organizational effects of hormones (long-lasting effects of hormones that persist in their absence) explain the difference.
But the significance of the molecular and biochemical sex differences will become clearer with further mechanistic dissection.
The strikingly consistent patterns of second primary cancers (SPCs) in German and Swedish populations provide excellent opportunities for joint studies and they also suggest that many underlying reasons for SPC may have universal and tangible causes that await mechanistic dissection.
The strikingly consistent patterns of SPCs in the two populations provide excellent opportunities for joint studies and they also suggest that many underlying reasons for SPC may have universal and tangible causes that await mechanistic dissection.
