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More broadly, mechanistic differences that can arise when investigating minimal antimicrobial units within larger naturally occurring CAMPs have not been rigorously explored.
However, there exist pharmacologic differences as well as other mechanistic differences that appear to favor torsemide use over furosemide.
Fourth, our data reveal some of the mechanistic differences that lead to NDJ vs. chromosome loss.
16 As CSCs and their more differentiated progenies share the same genetic background, we hypothesised that the apparent mechanistic differences that exist between CSCs and non-CSCs are related to a unique epigenetic signature.
"That's the state of the field we've produced a lot of good work, but there are so many types of disease, and they all have mechanistic differences that might be subtle or they might be profound".
The contrasts observed with purified monocomponent digestion; therefore, potentially highlight mechanistic differences that can perhaps be overcome in a synergistic mixture, especially where the mixtures generate much higher degrees of conversion of microcrystalline cellulose (i.e., >20% conversion).
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Then further mutations, including two active site mutations of Asp → Ala and His → Thr, gave rise to the mechanistic difference that characterizes the DDGS enzymes.
5) In HIV-1 clades C and F, the acidic dileucine in Vpu is positioned close to the membrane in helix 1. Can the authors speculate on possible mechanistic differences given that clade C Vpu's have been reported to localize differently?
Further, a simplistic examination of tumor-site concordance using differing study designs may not capture mechanistic concordance and susceptibility differences that can indicate carcinogenic potential.
While most transmissions resulted from a single infectious unit, multiple variant transmissions represent a significant fraction of transmission events, suggesting that there may be important mechanistic differences between these groups that are not yet understood.
In contrast, FADD-deficient mouse embryonic fibroblasts (MEF) are resistant to TNF-induced necroptosis in the presence of cycloheximide and caspase inhibitors, suggesting that mechanistic differences may exist between different cell types.
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