Sentence examples for mechanistic data were from inspiring English sources

In addition, new criteria allowing broader consideration of mechanistic data were added to the ROC.

Also, as there is scientific disagreement over the mechanism of OTA-induced renal tumors, mechanistic data were revisited.

Primary source studies examining any type of toxicity (e.g., reproductive, hepatic, cancer) in experimental animals and humans, in addition to toxicokinetic and mechanistic data, were identified.

Additional mechanistic data were provided, showing that VX-166 prevented lymphocyte apoptosis in vivo and decreased circulating levels of endotoxin and proinflammatory cytokines in both models.

In like fashion, regulators and risk assessors can be better equipped to apply mechanistic data if the concepts underlying mechanistic research and the limitations that must be placed on interpretation of mechanistic data are understood.

"The most appropriate and scientifically based evaluation of the cancers reported in humans and laboratory animals as well as supportive mechanistic data is that glyphosate is a probable human carcinogen," the report states.

We have also started adding small molecules to the PluriNetWork (data not shown), as stimulators or inhibitors of specific genes/proteins, wherever such mechanistic data are available.

To sum up, the phenotype of the Cry2 knockout mice together with mechanistic data are in line with the finding in this report suggesting that CRY2 has a role in winter depression.

Until more mechanistic data are available, we believe the second, noncausal explanation is more appropriate.

The schedule of events which includes completion of study questionnaires and collection of mechanistic data is described in figure 1.

Mechanistic data are then considered in order to determine whether they warrant a change from the preliminary classification.