Sentence examples for mechanistic course from inspiring English sources

We note that the mechanisms assumed for RNA coordinated to metal ion complexes follow this mechanistic course (a noncoordinated alkoxy nucleophile with a high p Ka value), so substituting the role of the 2′OH with a carbonyl hydrate site on the ligand provides a strategy for designing complexes effective for DNA hydrolysis as well.

Thermolyses of the adduct 32 and 34 exposed a further anomaly, with the former giving a 5 4 mixture of the quinone 35 and cyclopentenedione (E)- 36, while the a latter gave only the cyclopentenedione (Z)- 37. To gain insights into the mechanistic course of organoytterbium addition reactions we decided to initiate a computational study of the reaction of PhYb OTf 2 with 1 b.

His own theory of the origin of language is, no less than his approach to language as such, teleological in character rather than mechanistic and is of course supported by the psychology of intentionality.

Of course, such mechanistic hypotheses need further experimental verifications.

In order to understand the origin of the kinetic differences between s- and i-proteasomes we calibrate our mechanistic model against new time course data from s- and i-proteasomes.

Of course, a less mechanistic explanation for the observed relationship is that LWD is coincidentally correlated with some other habitat attribute that is responsible for selection on fry size.

A key challenge in this area is the automated inference (reverse-engineering) of dynamic, mechanistic GRN models from time-course gene expression data.

Connecting life-course studies with mechanistic research in well-phenotyped patients should provide much needed new insight into disease mechanisms and, hopefully, will lead to the identification of new therapeutic targets for disease prevention and treatment.

This requires the development of algorithms to provide more mechanistic insight by combining time-course expression data with parametric models of gene expression, and there has been some progress in this direction.

Yet, the mechanistic details involved in the reaction course of many enzymes that catalyze sterols still need to be worked out.

While much effort has been invested in the development of mechanistic models that replicate the time course of ECG changes, it is unclear how and at what point these will be used in the drug development process.