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We discuss how these results have both predictive and mechanistic consequences for understanding the success and failure of repair protein activity associated with such oxidatively sensitive, conformationally plastic/dynamic repetitive DNA domains.
This provides direct mechanistic consequences for immune activities driven by these transcription factors.
Formation of p-quinone structures from the p-dihydroxyl moiety could have multiple mechanistic consequences for the observed antiglycation properties of RIF and RSV in vitro.
The simultaneous loss of crossovers and interference has mechanistic consequences for the maintenance of crossover assurance in the msh4 –R676W hypomorph (see next section).
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These findings not only demonstrate the mechanistic consequences of S-nitrosation for these candidate proteins, but establish the full reversibility of the modification using the same selective reduction by copper II) and ascorbate employed for the SNO-DIGE method.
Taken together, the wide range of cellular mechanistic consequences of FASN inhibition provides potential for effective treatment of a large number of cancers of unmet need.
The results from electrogenerative reduction are discussed in terms of steric and mechanistic consequences of sulfur coverages.
Without additional studies on the mechanistic consequences of Fc receptor variation, these models cannot be eliminated.
This model for the first time explains the cortical origins and topography of endogenous action decisions, and the natural emergence of functional specialisation in the cortex, as mechanistic consequences of neurobiological principles, anatomical structure and sensorimotor experience.
The differences between the H3.3/H3.1 subgroups may be a result of distinct cells of origin for these tumours, or reflect a mechanistic consequence of the type of histone mutated.
Mechanistic consequences derived from these measurements are discussed.
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CEO of Professional Science Editing for Scientists @ prosciediting.com