Jones and Martienssen note in their paper that there must be additional improvements in high-throughput technologies, analytical techniques, computational capability, mechanistic studies, and bioinformatic strategies.
The mechanistic model and simulation capability illustrates the merits of this unique diagnostic approach with unprecedented holistic quantitative resolution for complicated cell degradation that seems hardly resolvable by other diagnostic methods.
Although the metabolism of pollutants in vivo is very complex and requires a wide range of enzymatic capability, a proposed mechanistic scheme is shown for how poplars and associated microbes might interact to affect the observed transformation products from this study.
The primary focus of this paper is on comparing the capabilities of several important mechanistic models introduced in the literature to predict the pressure gradient of gas liquid flow through a pipeline in low liquid loading condition.
Yet this profound and seemingly highly adaptive difference in learning capability has its simple mechanistic basis in the selective suppression of taste-mediated, but not postingestive, learning in the gregarious phase.
For example, incorporating the capability to predict the mechanistic impact of additional cellular processes, such as signaling and transcriptional regulation, at the genome scale in human tissues presents additional, significant challenges.
Although the correlations found through the Connectivity Map approach are an excellent starting point to gain insights into how the gene-expression signatures indicate aberrant cellular or physiological behavior, more detailed mechanistic studies are necessary to develop predictive capabilities.
While there are useful normative and descriptive typologies of integration policy regimes, the capability-aspiration framework offers a mechanistic typology of how policies are expected to influence integration outcomes of immigrants.
While the arrays show promise for improving diagnostic capability in breast cancers, ascribing mechanistic interpretations to correlative data should be done with extreme caution.
