Thus, while the induction of chronic inflammation is plausible as a mechanistic application, further work needs to be done to establish cause and effect.
The identification of immunoactive agents for clinical and mechanistic applications is a very active area of research.
We aim to provide fundamental mechanistic and applications of tribological biomaterials, while emphasizing the advantages and disadvantages of various kinds of tribological biomaterials.
Finally, prospective about the rational design, mechanistic understanding and application of BOC based materials is demonstrated, aiming to broaden the perspective and provide guidelines for future work.
This is often pursued by application of mechanistic models incorporating the underlying mechanisms.
In part I of applying mechanistic design patterns, the application of the adaptor pattern is very straightforward in the roadrunner portion of the exercise.
The application of mechanistic studies to drug discovery and development from traditional therapies is discussed, with an emphasis on preclinical toxicology assessments, pharmacovigilance, comparative effectiveness research, and the practice of "P4" medicine, particularly in the context of influenza, ischemic heart disease, stroke, and cancer.
Furthermore, our results emphasized the importance of the application of mechanistic approaches and the power of systems assessment to study toxicological responses in ecologically relevant organisms.
Through the continued development and application of mechanistic model-based drug development, we hope to see a new generation of highly selective and effective drug regimens emerge to better serve the needs of patients.
However, application of watershed mechanistic models to assess nutrient inputs is limited by large data requirements and intensive model calibration efforts.
