Sentence examples for mechanistic activity of from inspiring English sources
However, up to now, the role of DSBs and the phosphorylation of H2AX in response to SAG and its potential role in the mechanistic activity of SAG will need further investigation.
Despite its role in tumorigenesis, mechanistic activity of ΔNp63 mediated oncogenic function in osteosarcoma is poorly understood.
This will facilitate in exploring the mechanistic activity of the selected plants which will open up avenues for development of these plants as anti-diabetic agents.
This study also illustrates how allergen challenge proof-of-activity studies can be used to explore mechanistic activity of novel therapeutics prior to exposing a large number of patients to experimental therapies.
However, these findings warrant extensive studies on chemical profiles and mechanistic action of antiproliferative and antioxidant activities.
To determine the potential mechanistic anti-fibrotic activity of SAP on mesenchymal cells, we initially assessed the effect(s) of SAP on fibroblast proliferation, alone or in combination with known proliferative mediators.
Thus, the newly identified mechanistic and functional activity of group V sPLA2 suggests that its therapeutic administration is a potential novel treatment opportunity for those patients in which immune complexes have a prominent contribution to disease.
Our results provide a quantitative and mechanistic understanding of inhibitory activity of steroidal and azaheterocyclic AIs of relevance to adverse outcome pathway development and rational drug design.
A detailed understanding of the proximity and orientation of pivotal functional groups can reveal the molecular mechanistic basis for the activity of a protein.
This study of pyrophosphorolysis, along with our previous examination of polymerization, form the frame work for future understanding of the mechanistic basis of the activity of the Ty1 RT second site suppressor mutants.
Computational studies, as well as NMR and CD spectroscopy provide mechanistic insight into the activity of the compound which is most likely mediated by clamping of the aromatic recognition interface in the central segment of Aβ.
