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I am much inclined to believe that such mechanisms would explain how smallpox, syphilis, plague, yellow fever, etc. have come about in the course of time, and how certain great epidemics appear once in a while.
We speculate that these pathologic mechanisms would explain the death of pregnant females that do not show peripheral parasitemia but exhibit placental pathology.
Principally, two different mechanisms would explain the source of apoptotic tumor cells in BM aspirates.
Although Mudgal and Hastings [ 11] only considered intra-articular fractures, similar mechanisms would explain the occurrence of ligamentous injuries in extra-articular fractures.
To better understand whether common pathophysiologic mechanisms would explain these transcriptional changes in aged mice, we performed gene ontology (GO) analyses and visualized the data with Cytoscape [ 19].
It has been reported that TNF blockade severely impairs the induction of T cell-dependent humoral responses and, accordingly, may have a beneficial effect in antibody-mediated inflammatory pathologies [ 9] These pathogenetic mechanisms would explain the possible therapeutic effect of anti-TNF-α monoclonal antibody.
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Such a mechanism would explain 29% (99/344) of the buds that were detected just after mitosis (Fig. 3G).
This mechanism would explain increased Gag processing, as enhanced lipid raft-binding and Gag multimerization would in turn facilitate dimerization of Gag-Pol precursors within the assembling virion [92] and thus activation of the viral protease.
Such a mechanism would explain our ability to reverse fade rapidly (Figure 6) since desensitization due to phosphorylation takes only a matter of seconds and can presumably be reversed on the same time scale.
The involvement of a completely different molecular mechanism would explain why alleles of comm that completely lack the LSPY motif necessary for sorting are still able to induce crossing [9].
This transcriptional interference mechanism would explain the imprinted expression profile of Commd1_v1a.
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