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In order to investigate putative signaling mechanisms which activate gene and protein expression after androgen stimulation, we have applied our recently developed technique of topological significance analysis [24].
In addition to mechanisms which activate VSMC migration, there are endogenous mechanisms which maintain quiescence, thereby preventing migration.
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These results together with our previous study suggest that HPV16 modifies S6 kinase activation via mechanism, which activates S6 kinase downstream of Akt function.
The mechanism which activates squeal is still unexplained and will be analyzed in the paper at hand.
The phenomenon of persistence has been investigated in a host of microorganisms but the molecular mechanism which activates the switch to persistence in a cell is little understood in most cases.
Cisplatin induced CEBPD by an as of yet unidentified mechanism which activated the SOD1 gene expression.
Activation of AMPK by NEFA in catabolic tissues such as heart and skeletal muscle has been proposed to be a feedforward mechanism which activates the β-oxidation of FAs [ 6, 8].
The mechanisms through which activated PI3K mediates the transformed phenotype are incompletely understood and probably involve multiple targets.
A mechanism by which activated monocytes accelerate lung fibrosis has been reported through upregulation of PDGF [ 17].
It is important, therefore, to investigate the mechanism by which activated CB1954 kills NR-expressing cancer cells.
Peripheral blood macrophages play a pivotal role in the anticancer function of the immune system [1]– [3], but the mechanism by which activated macrophages kill cancer cells is unclear.
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CEO of Professional Science Editing for Scientists @ prosciediting.com