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A gentler approach involves carrier- and receptor-mediated transport mechanisms using endogenous nutrient transport systems within the BBB (Figure 1).
As the physiological energy conversion mechanisms using endogenous versus exogenous energy supplies are different in fish one might expect a rather different set of genes affecting growth before and after the start of active feeding [ 33].
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The ever-increasing genomic information and the elucidation of the molecular mechanisms that control fruit development could be exploited to confer the desired fruit phenotypes using endogenous DNA.
Data were normalised using endogenous RNU48 control.
While it is well established that nonenzymatic antioxidants such as ascorbic acid and glutathione are important in protecting ocular tissues from oxidative stress, less is known about the delivery mechanisms used to accumulate these endogenous antioxidants in the different tissues of the eye.
Together, these studies add validation to the presence of an endogenous mechanism used by the intestinal epithelium to dynamically regulate its paracellular permeability properties and better define the potential to enhance the oral delivery of biopharmaceuticals via a transient regulation of an endogenous mechanism controlling the intestinal paracellular barrier.
However, one major curiosity is whether the developmental mechanism used by the ectopic small micromeres is also used by endogenous small micromeres when they migrate during normal embryogenesis.
This information indicates that PPC, like IPoC, provides protection through endogenous mechanisms, but using at least partially different pathways than IPoC.
Physiological strategies are followed by applying endogenous transport mechanisms by using either carrier mediated transport of nutrients or receptor mediated transport of peptides.
Endogenous biotin was blocked using an endogenous biotin blocking kit.
To assess the functional role of GPCR signaling in pluripotent colony formation and, specifically, to determine if inhibition of Gi signaling disrupts endogenous organizing mechanisms, we used a scratch wound healing assay in which colony re-growth into a denuded area is monitored by time-lapse microscopy (Figure 3A).
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