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This methodology is based on a mathematical framework for carrying out systematic conceptual design of mechanisms using dual-vector algebra.
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Topological requirements are handled using dual-vector representation of stored building blocks and prescribed motion requirements.
In this paper, a method for determination of developable spherical orthotomic ruled surfaces is given by using dual vector calculus.
It also requires a 'two cylinder' mechanism using dual ATPase domains, consistent with two Res subunits.
Our results provide proof-of-concept of gene therapy for STGD and USH1B using dual AAV vectors.
The T. reesei expression cassettes shown in Figure 1 were excised from the cloning vectors using dual PmeI sites (Thermo) and transformed into T. reesei.
Overall, these results show tremendous promise of wt-p53 and miR-125b gene therapy using dual CD44/EGFR-targeting HA NP vector for effective treatment of lung cancer.
This has been used to characterise the degree of order and disruption in bilayers using dual polarisation interferometry to understand mechanisms of protein interaction.
These promoter reporter plasmids along with pRLTK (renilla luciferase vector) were transfected into RKO cells and luciferase activity was measured using Dual luciferase assay kit (Promega).
We prove the optimality of each mechanism using the dual program.
To determine which cell type in the retina expressed ABCA4, we used dual AAV OV vectors (dose of each vector/eye: 1 × 10 GC) that contained either the PR-specific RHO and RHOK, or the RPE-specific VMD2 promoters.
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