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The mechanisms underlying transition to SPMS are unknown and effective treatments and biomarkers are lacking.
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The discovery of convergence at two levels the phenotype and the genetic architecture associated with alternative social forms points at general genetic mechanisms underlying transitions in social organization.
The focus of this paper is to construct a computationally efficient model to study macroscopic biophysical mechanisms underlying transitions between different kinds of population firing.
The models presented in this study make the concept of probabilistic modelling of ontogenetic life-history transitions in continuous time more easily accessible, by offering easy-to-use tools for analysing transition data typically available from wild with little prior knowledge of mechanisms underlying transitions.
To decipher the molecular mechanism underlying transition from chronic liver injury to dysplasia, we investigated the oncogenic role of gankyrin (PSMD10 or p28GANK) during malignant transformation in a transgenic mouse model.
The precise mechanisms and biomarkers, underlying transition from renal dysfunction to nephrotoxicity, deserve better elucidation; experimental studies have been important to improve the knowledge on this translational issue of clinical relevance.
PMT may represent for GBM the equivalent of epithelial MES transition associated with other aggressive cancers; however, the molecular mechanisms underlying this transition remain elusive.
Molecular mechanisms underlying the transition toward the dilated phenotype are still not known.
Although the mechanisms underlying the transition from episodic to chronic TTH are not fully understood, the existing literature supports that sensitization mechanisms play an important role [4, 5].
We next investigated the possible molecular mechanisms underlying the transition to tumor growth induced by exposure to CSE.
Thus, this is a particularly suitable experimental system to investigate the molecular mechanisms underlying the transition from proliferation to neurogenesis.
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CEO of Professional Science Editing for Scientists @ prosciediting.com