Sentence examples for mechanisms underlying substrate from inspiring English sources
pH-dependence experiments showed that the mechanisms underlying substrate recognition for the sulfation of lithocholic acid (a bile acid) and 5α-petromyzonol (a bile alcohol) differed between the human SULT2A1 and the Zebra danio SULT3 ST2 and ST3.
However, mechanisms underlying substrate proteolysis by RseP remains elusive.
Further studies are required to elucidate the precise mechanisms underlying substrate choice pathways.
Many excellent comprehensive reviews have discussed the different phosphatase superfamilies, their evolution and the mechanisms underlying substrate recognition specificity [13 17,12].
Detailed knowledge of mechanisms underlying substrate discrimination and cleavage would help in controlling the cleavage of membrane proteins by I-CLiPs including S2P proteases.
Molecular mechanisms underlying substrate recognition and cleavage by Escherichia coli RseP, which belongs to S2P family of intramembrane-cleaving proteases, remain unclear.
The molecular mechanisms underlying substrate-induced endocytosis of nutrient transporters have been studied in great detail in yeast, with Gap1 serving as the main model system (Jauniaux and Grenson 1990; Lauwers et al. 2010; Magasanik and Kaiser 2002; Chen and Kaiser 2002) (Fig. 2a).
Here we present the molecular mechanism underlying substrate recognition in EmrE, a small MDT from Escherichia coli.
Even though the authors are not yet able to explain the molecular mechanism underlying substrate-dependent fluorescence quenching, this study opens up a new avenue to monitor in vivo activities of transporters and thus promises to be highly influential to this field.
Our identification of many new putative substrates should enable experiments to understand better the mechanisms underlying BACE1 substrate selection and what role β-secretase processing plays in modulating a particular substrate's function.
In spite of their pharmacological importance, still little is known about their higher structural organization and the molecular mechanisms underlying the substrate translocation process.
