Sentence examples for mechanisms underlying progression from inspiring English sources

Although the mechanisms underlying progression in these diseases are unknown, increasing evidence supports a model where misfolded proteins released from a cell harboring pathological inclusions act on recipient cells to form de novo pathology by corrupting endogenous normal proteins to adopt pathological conformations.

We believe that the main objective of studies carried out in experimental models of cerebral ischemic injury must be a better understanding of the fundamental mechanisms underlying progression of the ischemic injury.

The mechanisms underlying progression to CRPC are unknown.

The mechanisms underlying progression to cardiac hypertrophy remain poorly understood.

While the cytogenetic landscape of tumours is well known, the molecular mechanisms underlying progression and recurrence are not well defined.

Hence, a greater understanding of ADT-driven molecular changes may yield information on the mechanisms underlying progression to CRPC.

We demonstrated that dramatically different molecular mechanisms underlie progression to resistance to tamoxifen (henceforth, MCF7-T) and fulvestrant (henceforth, MCF7-F) and also identified specific genes and biochemical pathways associated with SERM- and SERD-resistance.

NGS based studies through whole genome sequencing (WGS) and whole exome sequencing (WES) technologies will help us to understand the mechanism underlying progression and evolution of cancer (6).

The molecular mechanisms underlying CRPC progression are unclear.

Thus, understanding the pathological mechanisms underlying the progression of hepatic steatosis is important for identifying new therapeutic targets against NAFLD.

White is using this technology to study the mechanisms underlying the progression of breast, prostate, brain, and lung cancers.