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Accordingly, cells have multiple mechanisms to reverse damaging DNA modifications.
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Speaking at an Atlantic Council event last month, French Ambassador to the U.S. Gérard Araud said that the French negotiators had floated a mechanism to reverse the veto power.
Furthermore, the authors report that endothelial cells in the heart possess an intrinsic mechanism to reverse aberrant DNA promoter methylation involving TET3-mediated hydroxymethylation.
Rap inhibits cell growth by dephosphorylation of p70S6K and 4E-BP1 [ 8, 26], and dephosphorylation of 4E-BP1 is the key mechanism to reverse GC resistance [ 4].
In conclusion, the knowledge of the mechanisms, aimed to reverse the phenotype of DCs from an immunosuppressive to an immunostimulatory cell type, may be relevant to guide the design of more efficient protocols for cancer immunotherapy and to identify possible candidates for DC-based immunotherapy.
The mechanism belonged to reverse atom transfer radical polymerization (reverse ATRP).
Co-delivery of chemotherapeutic drugs and small interfering RNA (siRNA) has been developed because of its ability to generate synergistic anticancer effects via different mechanisms of action, to reverse MDR and increase the efficacy of chemotherapeutic drugs in cancer therapy.
(4) It is urgent to discover novel mechanisms and targets to reverse the resistance of pancreatic cancer to chemotherapy.
In tandem, these acute and chronic mechanisms are expected to reverse elevated triglyceride storage, increase insulin sensitivity, and improve glycemic control in the liver [ 42].
This may infer that the macrophage is responding to the products secreted from CC cells by increasing TLR-mediated signaling in an attempt to establish compensatory mechanisms in order to reverse the process that induces a phenotype suppressor.
The REDD+ mechanism is designed to reverse this situation and create opportunities for necessary reforms both inside and outside the forestry sector.
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