Although more studies are required to clarify this complex regulatory mechanism, we want to emphasize some aspects.
We changed the mechanisms of navigation, however, to emphasize prediction/anticipation rather than reaction.
Though Skyrms occasionally uses the replicator dynamic, both tend to emphasize simpler mechanisms in an agent-based learning context.
Regarding validation of the proposed mechanisms, we would again like to emphasize that apart from a time dependence dynamics method, such as MD simulations, no other experimental technique exists at present that can be used to validate these mechanisms.
Decitabine or 5-azacytidine dose and schedule can be rationalized to emphasize this mechanism of action, as an alternative or complement to conventional apoptosis-based oncotherapy.
This feature is particularly important to emphasize that several mechanisms may be acting simultaneously on a single population.
It is also important to emphasize that this mechanism is very different from that found in budding yeast where the myosin uses actin filaments of opposite orientation to pull the nucleus toward the bud neck.
One response to this criticism is to emphasize the conserved genetic mechanisms shared by all animals despite differences in developmental phenomena (Gerhart and Kirschner 2007; Ankeny and Leonelli 2011; Weber 2005).
This interpretation is supported at least by the long-wave theorists' tendency to emphasize the long wave mechanism as contingent on the decisions and choices made by various actors in the socio-economic system [23].
