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Simulation results show that with these mechanisms, the data packet delivery ratio achieves more than 90% even in hard and difficult scenarios of very sparse or very dense networks, and the end-to-end delay and energy consumption per delivered packet are reduced.
Regardless of the specific mechanisms, the data indicate that cytosine-deamination may be a general mechanism of DSB generation in mammalian cells.
Related to the first assumption on the presence of governance mechanisms, the data indicated that relational governance was supplemented with either hierarchical or contractual governance, or both, in 19 of the 22 cases.
Using aged mouse cohorts or patient samples allows for studying the physiological processes of aging but as to tissue-specific and cell-intrinsic mechanisms, the data will always be impacted by the systemic confounders.
In conclusion, regardless of the mechanisms, the data of our study clearly demonstrate that HBc not only has the ability to bind to a large number of gene promoters in the human genome, but also has the ability to disrupt cellular gene expression of HBV-infected hepatocytes.
Data integrity is ensured by the following mechanisms: the data is encrypted during transmission (data modification would imply correct decryption and correct encryption after modification, which is not easily possible); incomplete or modified transmissions can be detected and notified; currently there are no known viruses and other compromising software affecting iOS [ 20, 21].
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Regarding the failure mechanism, the data was classified into four categories: shear-dominated (SH), flexure-dominated (F), sliding (SL) and hybrid (H), i.e. combined shear and flexural, failure modes.
Although the sum of these results do not conclusively rule out an indirect modulatory mechanism, the data in total strongly favor PBA directly interacting with the KCNQ pore forming subunit.
To confirm the diffusion mechanism the data was fitted into Korsemeyer-Peppas equation.
Although transcriptional regulation is the most obvious caretaker mechanism, the data instead support HDAC stabilization of the non-histone protein Sae2, a nuclease.
While we agree that in your current paper you have sought to search for the mechanism, the data provided is not convincing.
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