Due to the complex inter-connectivity of the EGFR signaling network, it is difficult to identify conserved signaling modules and those specific control mechanisms that modulate the strength of EGFR signaling [ 3].
Elucidating cellular mechanisms that modulate the N-linked glycome is, therefore, crucial.
There is thus a need to map, in detail, the SCF/c-Kit interaction sites and the mechanisms that modulate this interaction.
Chronic elevation or reduction of network activity activates compensatory mechanisms that modulate synaptic strength in the opposite direction (i.e. reduced network activity leads to increased synaptic strength), a process called homeostatic synaptic plasticity.
Here, we used a paired experimental design in the zebra finch (Taeniopygia guttata) to examine the hormonal mechanisms that modulate parental behavior and reproductive success in response to a partnership change (hereafter divorce).
This article outlines the processes underlying oxygenic photosynthesis in land plants, the regulatory mechanisms that modulate photosynthetic light reactions in response to environmental changes, and the strategies and adaptations used by photoautotrophs to maximize CO2 fixation.
The physical mechanisms that modulate the coupling (local cooperativity) among amino acid residues on the extensive binding surface of RBD1 are investigated here, using mutants that replace a highly conserved glycine residue.
It is convenient to think of these processes in terms of local feedback mechanisms that modulate synaptic currents.
However, communication among neurons appears to change dynamically [1], suggesting the presence of not-yet understood network mechanisms that modulate the effective strength of a given connection.
Dr. Spurney's research has focused on the role of G protein coupled receptors (GPCRs) in regulating cellular physiology both in normal and disease states as well as the regulatory mechanisms that modulate GPCR responsiveness at the molecular level.
The Spurney Lab has focused on the role of G-protein coupled receptors (GPCRs) in regulating cellular physiology both in normal and disease states, as well as the regulatory mechanisms that modulate GPCR responsiveness at the molecular level.
