The clear understanding of the full mechanism requires additional studies.
FGFR3 overexpression may provide a positive effect by preventing progression to MI disease; the loss of this potentially protective mechanism requires additional studies.
This is consistent with sex differences in brain development and rates of maturation that have previously been observed by magnetic resonance imaging in slightly older children (6 17 years of age) [ 41] and represent a possible regulatory mechanism requiring additional investigation.
This relationship is complicated in soils by chemical and physical protection mechanisms, which require additional energies to overcome for decomposition to occur.
Validation of this mechanism will require additional work.
These two possibilities are not easily differentiated and clarification of the exact mechanism will require additional biochemical and structural studies.
Although elevating PI3K signaling does rescue the defects in pdgfra mutants, understanding the precise mechanism will require additional studies.
The actual mechanism would require additional studies on the enzymes encoded by the genes in the bref cluster.
Although the sex bias in first eggs is consistent with the idea of sex-specific follicle abortion, such a mechanism would require additional developed follicles to replace the first follicle in case of abortion.
In summary, the structural and functional data presented here have allowed us to propose a detailed mechanism for RelE-mediated mRNA cleavage on the ribosome; however, a full understanding of all aspects of the reaction mechanism will probably require additional work by complementary techniques.
