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The experimental data have been compared with the model predictions of four detailed kinetic mechanisms previously reported in the literature.
Similarly, the most significant GO categories or pathways in the analysis of underexpressed genes were "gene expression" and others related to protein biosynthesis mechanisms previously reported [ 32].
As shown in Table 3, N-of-1 pathways discovered the most common and highly related mechanisms previously reported [ 8, 9, 26] as associated to molecular and cellular phenotypes that are triggered by PTBP1 depletion such as GO 0000398, mRNA splicing via spliceosome and GO 00010564, regulation of cell cycle process.
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Rapamycin eliminated BDE-4 triggered BDE-4 triggeredthout inhibiting caffeine-induced Ca2+ release, indicating that PBDEs sensitize RyR1 via a mechanism previously reported for PCBs.
The resulting SO3− is known to react further with molecular oxygen to form −O3SOO and SO4 − in the free radical chain mechanism previously reported (Hayon et al. 1972; Mottley and Mason 1988; Reed et al. 1986).
Quantification of absolute cell numbers was not used because the number of cells expressing the reporter can differ between individual animals due to the variability of reporter response potentially caused by an epigenetic mechanisms as previously reported (Sakai and Dräger, 2010).
The extrusion algorithm used in the simulations has been selected from a number of alternative mechanisms by comparing each mechanism with previously reported experimental data from glass networks.
Apart from the implications discussed below, our study confirms that DHE can inhibit the vasodepressor sensory CGRPergic outflow in pithed rats by prejunctional mechanisms, as previously reported by Lozano-Cuenca et al. [16].
Background: Mechanisms underlying previously reported air pollution and cardiovascular (CV) morbidity associations remain poorly understood.
Pathophysiologic pathways proposed as mechanisms underlying previously reported PM/MI associations include systemic inflammation, endothelial dysfunction, disturbance of autonomic tone, and enhanced coagulation/thrombosis (Brook et al. 2004).
Because MIAMI cells secrete repair-mediating cytokines, they provide an excellent model for future studies on the mechanisms of previously reported decreases in in vivo vascular repair [ 16].
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