Sentence examples for mechanisms of sensitivity from inspiring English sources
The CNM in the present study is further constrained to contain only those subnetworks that are supported by the observed changes in all sensitive cell lines: it represents the common set of hypotheses for mechanisms of sensitivity to GSK690693.
Zhao, Y. et al. High-Resolution Mapping of RNA Polymerases Identifies Mechanisms of Sensitivity and Resistance to BET Inhibitors in t(8 21) AML.
To further understand the mechanisms of sensitivity to SQLE inhibition, we used a CRISPR-based suppressor screen to identify genes that, when inactivated, can lead to NB-598 resistance.
In addition to correlating pre-treatment molecular characteristics to responsiveness to such therapy, serial tumor tissue collection in some patients (before treatment, and at time of response and/ or resistance) will further allow assessment of changes in the tumor that can help elucidate mechanisms of sensitivity, primary resistance and acquired resistance to therapy.
These studies will not only define mechanisms of sensitivity versus resistance to these newer agents, but also inform the design of combined therapy protocols to enhance cytotoxicity, overcome drug resistance, and improve patient outcome in MM.
These include the need for more tissue-based studies to allow us to understand the mechanisms of sensitivity and resistance within and across subtypes, and the need to revisit risk and prevention by subtype.
Multiregimen drug testing, paired with next-generation sequencing before and after therapy and timed tumor pharmacodynamics enables determination of efficacy, signaling pathway alterations, and mechanisms of sensitivity-resistance in individual models.
Proliferating hybrid clones of sensitive and resistant cells remained sensitive to ABHA, indicating a dominant-negative mechanism of sensitivity.
The theory of multilayer-thin-film interference is introduced to explain the mechanism of sensitivity.
The mechanism of sensitivity of alumina ceramic strength to the thermal shock damage at elevated temperature was analyzed by the microstructure of the facture surface with SEM images.
It is known that the depletion layer plays a key role in the mechanism of sensitivity.
