Sentence examples for mechanisms of secretion from inspiring English sources

The present study, therefore, reports the presence of CT-1 and gp130 in vascular endothelial cells and mechanisms of secretion of ET-1 related to this cytokine system.

Some members are also secreted from cells exerting cytokine-like paracrine or autocrine functions although the precise mechanisms of secretion are still being elucidated [3] [5].

Since both the cellular source of serum TRAIL and the mechanisms of secretion of soluble TRAIL are incompletely understood phenomena [7], [24], it is unclear whether the significant decline in the serum levels of TRAIL reflects a deficit of production or an increased consumption of TRAIL in the acute phase after AMI.

Our understanding of the molecular mechanisms of secretion and the genetic regulation of granule biogenesis still remains incomplete.

SNAREs were first identified in platelets in 1997 [60], and since then, our understanding of the mechanisms of secretion has increased tremendously (see Fig. 2).

These mechanisms of secretion offer an explanation for the marked stability of miRNAs in the blood stream, due to shielding of the associated miRNAs from RNAse-activity.

The major limitation is that the regulatory mechanism of miRNA is intracellular; the number of proteins secreted into circulation and the regulatory mechanism of secretion are unknown.

Here we show that HGG growth depends on microenvironmental NLGN3, identify signalling cascades downstream of NLGN3 binding in glioma, and determine a therapeutically targetable mechanism of secretion.

The pro-forms of interleukin-1β (IL-1β) and IL-18 are processed by caspase-1 and released during pyroptosis, although the exact mechanism of secretion remains controversial.

Although it lacks a signal peptide and its mechanism of secretion is unknown, extracellular annexin II has recently been found in several tissues as both soluble and membrane-bound protein.

In contrast to the α and β toxins, δ toxin does not possess a cleavable signal sequence [27], and its mechanism of secretion is not completely understood.