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The conditions of structure refinement up to ultrafine and nanocrystalline levels as a result of both shear and diffusion mechanisms of reverse α-γ transformation are determined.
Because of its detailed predictions of lipid-associated apo A-I structure, this molecular belt model, if confirmed, provides a blueprint for understanding the molecular mechanisms of reverse cholesterol transport, and thus for the rational design of new classes of drugs for reversal of atherosclerosis and cardiovascular disease.
Both of these variants disrupt the molecular mechanisms of reverse transport of DA, resulting in DA dysfunction and associated behavioral abnormalities.
Moreover, the authors showed that another autism-causing rare variant in the syntaxin 1A gene (STX1A), which converts Arg26 to glutamine (STX1A R26Q), disrupts the molecular mechanisms of reverse transport of DA.
If the mechanisms of reverse migration could be identified, then targeting these mechanisms might offer an effective treatment to alleviate diseases, such as chronic obstructive pulmonary disease, by removing inflammation, rather than by treating the symptoms alone.
However, this difference can be attributed to the different normalization procedures on the array, i.e. based on the overall mean, or in the qPCR data, i.e. based on housekeeping genes, as well as on the the different mechanisms of reverse transcription that is used for qPCR and expression arrays.
Similar(54)
A huge amount of rank formulas associated with reverse-order laws of generalized inverses of products of matrices have been established since the 1990s, which played essential roles in revealing mechanisms of reverse-order laws.
Diffusionless mechanism of reverse α-γ transformation of the investigated alloy occurs at the heating of quenched alloy in the interval of this α-γ transformation with critical rate 70 °C/s.
However, in spite of all these attempts, the exact mechanism of reverse propagation still remains unclear.
As a result of the particular mechanism of reverse transcription of LTR retrotransposons, both LTRs of each element are initially identical at the time of insertion (Telesnitsky and Goff 1997).
The mechanism of reverse polymerization is presumed to involve nucleophilic attack of the 3′-OH from each incoming NTP on the intact 5′-triphosphate created by the preceding nucleotide addition.
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