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The purpose of this study was to examine the elderly recidivist cohort at an urban trauma center for mechanisms of repeat injury.
The molecular mechanisms of repeat instability, regarding contractions and expansions, are mediated by DNA replication, repair and recombination, probably concerted [14].
This variation between species and between amino acids in the chi-squared values shows that there is considerable variation in the mechanisms of repeat expansion and selection between eukaryotes and suggest that lineage specific distributions of SAARs might be a general feature of eukaryotic evolution.
Molecular mechanisms of repeat removal in copepods remain unexplored.
Understanding the mechanisms of repeat instability is crucial to arresting or reversing disease.
Identifying the functional roles of existing TNR sequences is a crucial step in understanding repeat variability, and expanding such knowledge across multiple species provides valuable background knowledge in selecting model organisms for studying the mechanisms of repeat variability.
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The data obtained so far strongly support the statement that the Th, Dat1 and Snca genes in the VTA are involved in the mechanisms of repeated aggression.
This indicates that normal alleles up to 18 ATTCT repeats originated by a single step mechanism of repeat length mutation.
Surprisingly higher order Markov models are needed to explain repeats, as this was expected to be a feature of secondary structural elements, but this in fact simply reflects the mechanism of repeat expansion.
According to our knowledge, no estimate has been provided yet for the mutation rate of Y chromosome penta- or hexanucleotide STRs, although it is intuitively obvious that the figure should be lower than that of STR loci with smaller repeat unit sizes, since replication slippage, the mechanism of repeat count changes of STRs, is less likely to occur in case of longer repeats.
While Δ gna2 does not show a discernible phenotype, sporulation is increased in Δ gna3 and Δ rid1 is of particular interest, because in this mutant the mechanism of repeat induced point mutation (RIP) is likely to be perturbed.
More suggestions(15)
means of repeat
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