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These data suggest that NASH and CKD share common proinflammatory and profibrotic mechanisms of progression, which are targeted incompletely by current treatments.
Mechanisms of progression toward diabetes cannot be definitely stated from this study.
Lastly, finding for driving mechanisms of progression is one of the ultimate goals in this field.
The alteration profiles in these 3 types of samples were different, suggesting distinct mechanisms of progression.
To be able to predict the persistence of the disease, we need to better understand its mechanisms of progression.
Initiating factors and underlying mechanisms of progression of this type of liver disease have not yet been elucidated.
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This has both made it difficult to diagnose NAFLD and to identify the mechanism of progression from simple steatosis to NASH, exacerbated by its complicated pathogenesis.
Although its cause and mechanism of progression are not well understood, various in vitro and in vivo experiments have proved that the decreased activity of the cholinergic neuron is responsible for the memory damage that is observed in these patients.
This information may uncover the critical mechanism of progression of liver fibrosis.
Liver fibrosis and HCC development are strongly correlated, but there is no effective treatment against fibrosis because the critical mechanism of progression of liver fibrosis is not fully understood.
Therefore, the CG model is probably inadequate to analyze the mechanism of progression of peritoneal injury.
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means of progression
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