Potentially critical differences exist between biological mechanisms of post-traumatic, age-associated, and metabolic phenotypes of OA.
Different mechanisms of post-transcriptional regulation, which can act individually, synergistically, or even in an antagonistic manner have been described.
To explore potential mechanisms of post-transcriptional regulation, changes in expression of seven targeted miRNAs, previously associated with basal γ-globin expression were examined using miScript primer assays.
It is difficult to speculate on the mechanisms of post-infectious headache, as current knowledge of the pathophysiology of even classical primary headache disorders is limited.
Understanding the neurobiological mechanisms of post-traumatic stress disorder (PTSD) is of vital importance for developing biomarkers and more effective pharmacotherapy for this disorder.
Chronic pain models provide support for the role of glutamate regulation in the dorsal horn of the ascending pain pathway [55], and remains an important area to develop for understanding the mechanisms of post-traumatic headache.
Pathophysiological mechanisms of post-traumatic headaches remain largely unclear as a reason to the epidemiological data suggesting, that mild injury to the head represents a greater risk of developing persistent headache.
Richard Meagher and his laboratory colleagues examine the molecular cytology of several ancient families of cytoskeletal proteins, the phytoremediation of environmental pollutants, and novel mechanisms of post-transcriptional gene regulation.
These specific CRM1 inhibitors are of interest as tool for analyzing the mechanisms of post-transcriptional control of gene expression and provide insight in the design of new agents.
In order to try to gain a better understanding of the mechanisms of post-operative pain, this study was designed to psychophysically determine physiological and pharmacological characteristics of experimental pain induced by a 4-mm-long incision through the skin, fascia and muscle in the volar forearm of humans.
