Sentence examples for mechanisms of dose from inspiring English sources

Our belief is that basic research should focus on means to target tolerogenic APC; to promote, for example through the use of appropriate adjuvants, secretion of IL-10 from both APC and T cells; and to investigate the mechanisms of dose escalation tolerance.

It was concluded that the physical mechanism of dose enhancement was caused by photoelectron delocalization from the cytosol to cell organelles, meaning that the dose enhancement effects were not limited to the vicinity of the nanoparticles (McNamara et al. 2016).

Combination therapies include widely used chemotherapy, biological products, and radiotherapy; it is necessary to gather specific information on mechanisms of action, doses, and dosing regimens in terms of interaction of immunotherapies with concomitant medications as much as possible.

8 To investigate the mechanism of dose-dependent and time-dependent PK nonlinearity for BMS-911543, a PBPK modeling methodology was applied, which enabled the bidirectional translation (forward and reverse translation) of the compound's ADME information.

These articles documented that the mechanisms of biphasic dose responses were clearly established to the level of receptor and, in a number of cases, to further levels of molecular detail.

The current level of knowledge about biological mechanisms of carcinogenesis dose not usually permit the confident assumption of a simple model, however; thus frequently the choice is between unstable risk estimates obtained using general models and statistically stable estimates whose stability depends on arbitrary model assumptions.

Thus these studies provide evidence for two mechanisms of the dose-limiting toxicity for bryostatin.

This indicated that neutropenia was one of the mechanisms of the dosing time dependent toxicity of gemcitabine±CDDP.

Our connectivity analysis provides strong in vivo support to the notion that excessive striatal responsiveness to levodopa and aberrant striato-cortical connectivity are key mechanisms underlying peak-of-dose LID in patients with Parkinson's disease.

What is the mechanism of large dose CDTHD in treating cholestatic hepatitis?

This evidence highlights the interest for further investigation about the mechanism of low dose collagen and its relevance in osteoarthritis therapy.