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Mechanisms of avoiding conflict through the reduction of unwanted interactions (both face-to-face and through line-of-sight) include spatial and temporal channelling of movement that regulate mobility (Al Huzil 2012), and different forms of seclusion ranging from high fences around residential lots to strict dress code for women (the veil being a symbolic form of seclusion).
The mechanisms of avoiding host digestion remain largely unknown, although some studies suggest that persistence may be due to the failure of phagosome-lysosome fusion [ 3- 6].
Because redfronted lemurs also reconcile soon after a conflict to reduce the probability of further attacks (Kappeler 1993), similar mechanisms of avoiding conflicts have evolved in strepsirrhine and anthropoid primates.
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This reveals the mechanism of avoiding the futile cycling caused by Ppc and Pck during gluconeogenic phase [129], where ATP generation becomes important.
These data suggest that unlike with some other tumor-selective agents such as TRAIL receptor-targeted drugs, where true resistance can be achieved by inhibiting apoptosis [20], it may be more difficult for tumor cells to evolve a mechanism of avoiding targeted toxin-induced death.
Developing drug candidates that could potentially inhibit ABC transporters at the transcriptional level would be an effective mechanism of avoiding drug resistance and could also be an excellent approach to target CSCs which overexpress these efflux pumps.
Second, like most plants, A. thaliana possesses a number of mechanisms for avoiding high temperatures that cannot be used at the seedling stage because the necessary structures and functions simply are not present.
Except these mechanisms of CTC avoiding NK cell lysis, other mechanisms of tumour cell resistance against NK cells are requisite to be elucidated.
Replication is one of the main sources of spontaneous mutations despite the evolution of mechanisms to avoid mutations and maintain unchanged DNA sequences.
In addition, one of the mechanisms to avoid the shortage of liver grafts for transplant is the use of marginal livers, which may show higher risk of primary non-function or initial poor function.
It stipulates, among other things, standardised forms that all patent offices must accept, basic standards for electronic submission of patents, and mechanisms to avoid loss of rights due to non-essential formalities or unintentional delays.
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