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These observations will enable a broader understanding of the range of activity of EWS/FLI1 and will add to the growing literature on non-canonical mechanisms of activating HH-GLI signaling[30].
Mechanisms of activating NFκB may or may not involve the IκB proteins [ 36, 37].
Based on these observations, two possible mechanisms of activating these osmosensors have been proposed.
These differences stem from the mechanisms of activating plasminogen by these compounds.
In addition, they provide solid motivation to search for additional mechanisms of activating TorC1 or TorC1-independent mechanisms of regulating Gln3 localization and function in response to changes in the nitrogen environment.
Finally, the EGFR gene mutation may be lost in some cancer cells with other additional mechanisms of activating Akt.
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The generation mechanisms of complex fracture mesh and the mechanism of activating existing natural fractures during shale fracturing are studied based on rock fracture dynamics.
Recent reports indicate that mitotic myoblasts utilize an alternative mechanism of activating caspases [6].
A mechanism of activating the alternative pathway via mannose-binding protein in the MB lectin pathway was excluded [ 30].
We will now show how it is possible to combine the insight in curvature stress and the physical chemistry of lipid bilayers with an understanding of the mechanism of activating s-PLA2 in order to construct a liposomal drug-delivery system that may remove a critical bottleneck in the use of liposomes for cancer therapy.
Drug resistance is also mediated by defects in intrinsic cellular safeguard mechanisms capable of activating apoptosis.
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