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Although, for some compounds a deviation from the correlation suggests that other transport mechanisms may coexist.
Different drug resistance mechanisms may coexist within different metastatic lesions of individual patients.
In this regime, multiple transport mechanisms may coexist, including multistep hopping, fast carrier injection followed by partially coherent transport, and mechanisms determined by initial state preparation.
Moreover, considering that different resistance mechanisms may coexist in the same tumour, combination with other targeted agents with a potential for synergistic activity might be recommendable to restore sensitivity to trastuzumab.
However, identification of the pathophysiological mechanisms responsible for distinct pain syndromes is incomplete at present, and multiple mechanisms may coexist in many pain conditions, so combination therapy is often indicated 18.
In addition, using mechanistic approaches such as these, it has been seen that anti-apoptotic resistance mechanisms may coexist with a high level of pro-apoptotic potential, a situation termed 'primed for death'.
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Similarly, both telomerase-dependent and independent mechanism may coexist in the iPSCs reprogramming process.
A second mechanism may coexist to promote a U-shaped behavioural response to dopaminergic therapy, with anatomically distinct networks supporting separate elements of complex cognitive tasks.
In summary, both of the hypotheses on the underlying mechanisms of restructuring may coexist and are not contradictory.
These mechanisms, mainly involved in cell proliferation, may coexist with those affecting cell death.
Different symptoms (i.e., allodynia, burning or paroxysmal pain) may coexist in the same patient and may reflect different mechanisms of disease [ 10].
More suggestions(15)
mechanisms may underlie
mechanisms may change
mechanisms may underpin
mechanisms may account
mechanisms may take
mechanisms may differ
mechanisms may reduce
mechanisms may offset
mechanisms may exist
mechanisms may play
mechanisms may activate
mechanisms may relate
mechanisms may participate
mechanisms may help
mechanisms may function
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