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In contrast, the TME supports multiple mechanisms leading to the development of alternatively activated characteristics in TAMs.
The mechanisms leading to the development of epilepsy (epileptogenesis) are unknown.
We discuss the mechanisms leading to the development of corrugations as well as their different implications.
The Blenis lab is also investigating the molecular mechanisms leading to the development of drug resistance to targeted therapies with the goal of discovering how to overcome resistance.
Further phenotypic and functional characterizations of such subsets are needed to better understand the underlying molecular mechanisms leading to the development of these diseases.
By specifically focusing separately on the pre-growth or holding period and the growth or pulling period, the critical roles of each in the establishment of initial conditions and the competition between eutectic initiation mechanisms, leading to the development of a steady-state eutectic front, are examined.
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Thus suggesting that molecular mechanism leading to the development of AC of the small intestine may be different than those leading to CRC.
The results indicate that underlying molecular mechanism leading to the development of early – as opposed to late – metastases differ substantially.
Tissue damage mediated by ROS, or oxidative stress, is implicated as a potential molecular mechanism leading to the development of atherosclerosis [ 3].
Previous studies had documented that the AGEs accumulation induces cardiomocyte apoptosis, leading to caricardiomocyte loss, is one of major mechanism leading to the development of heart dysfunction in diabetic cardiomyopathy [ 7].
Currently, there is a lack of understanding of the molecular mechanisms leading to the development and progression of osteosarcomas.
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