Sentence examples for mechanisms involve activation from inspiring English sources
Putative downstream signaling mechanisms involve activation of transforming growth factor- β (TGF- β).
The anti-HBV mechanisms involve activation of JAK-STAT signaling and increase of the anti-HBV protein OAS expression.
It has been asserted that higher concentrations of BCAA in obesity cause or exacerbate insulin resistance through mechanisms involving activation of the molecular target of rapamycin (mTOR)[8].
Exogenous Gal-1 reduced the viability of enterocytes through apoptotic mechanisms involving activation of both caspase and mitochondrial pathways.
Gem also induces ROS which upregulate CXCR4 levels in PCCs via mechanisms involving activation of NF- κB.
We observed that rapid exposure to low-dose BPS had proarrhythmic impact on female rat hearts through mechanisms involving activation of ERβ signaling and alteration of myocyte Ca2+ handling.
Labdane diterpenes (T1 and T2) also exerted cardioprotective effects against A/R-induced injury in isolated cardiomyocytes and the mechanisms involved activation of specific survival signals (PI3K/AKT pathways, ERK1/2 and AMPK) and inhibition of apoptosis.
The effect of FVIIa on cytokine-induced beta cell death was not changed by inhibition of p38 or ERK but was abolished in the presence of JNK inhibition, suggesting that TF/FVIIa mediates beta cell death in response to cytokines by mechanisms involving activation of the stress kinase JNK (Fig. 6c).
Matrix metalloproteases (MMPs) comprise a family of enzymes that cleave protein substrates based on a conserved mechanism involving activation of an active site-bound water molecule by a Zn2+ ion.
Current research suggests that several of the obesogenic compounds act via a mechanism involving activation of peroxisome proliferator-activated nuclear receptors (PPARs) during perinatal development (Janesick and Blumberg 2011).
One mechanism involves activation of the heterotrimeric AMP-activated protein kinase (AMPK), a cell-autonomous sensor to energetic changes regulated by ATP to AMP ratios.
