Sentence examples for mechanisms including promoter from inspiring English sources
In transient expression experiments reduced protein expression can occur through various mechanisms including promoter squelching.
A number of molecular mechanisms including promoter competition, insulators and chromatin looping are thought to play a role in regulating these interactions.
Invasion is likely to be triggered by inactivation of the wild-type CDH1 allele through mechanisms including promoter hypermethylation [ 6].
Inhibition of the key metastasis suppressor E-cadherin can occur through a variety of mechanisms, including promoter hypermethylation of EMT-inducing factors, 31 or the action of microRNAs.
Furthermore, the acetyltransferase function of SAGA could affect gene expression by several mechanisms including promoter specific modification, global histone acetylation, factor acetylation, acting at PIC formation or at elongation [ 19].
Some possible mechanisms include promoter efficiency through transcription factor binding and alternative or false splicing.
In terms of the epigenetic control of E-cadherin expression in the head and neck cancers, the most frequently reported mechanism includes promoter DNA hypermethylation and overexpression of the target microRNA.
At the other end of the complexity spectrum are physical models mimicking the biological mechanisms at play, including promoter recognition, mRNA transcription and protein translation.
Isoform-specific transcripts can arise from different molecular mechanisms, including alternative promoter usage, alternative pre-mRNA splicing, alternative polyadenylation or alternative mRNA degradation [reviewed in [ 5]].
Our results demonstrate that diverse mechanisms including WIF1 promoter hypermethylation and loss of heterozygosity contribute to WIF1 downregulation in human salivary gland tumors.
It has been shown that some lncRNAs regulate the expression of genes in a close proximity (cis-acting) or in a distance (trans-acting) in the genome via a number of mechanisms, including modifying promoter activities by nucleosome repositioning, histone modifications, DNA methylation, activating/gathering/transporting of accessory proteins, epigenetic silencing and repression [ 8, 11, 12].
